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Updated: May 16, 2025

Differentiation of Mouse Breast Epithelial HC11 and EpH4 Cells
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疾病相关的STAT5B SH2域突变调节细胞因子驱动的增强器功能和乳腺发育

Hye Kyung Lee1, Jakub Jankowski2, Chengyu Liu3

  • 1Section of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD, 20892, USA. hyekyung.lee@nih.gov.

Journal of mammary gland biology and neoplasia
|March 31, 2025
PubMed
概括

人类STAT5B基因突变影响乳腺发育和哺乳. Y665H突变导致哺乳失败,而Y665F加速乳腺生长,突出了STAT5B.

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