相关实验视频
Updated: May 16, 2025

04:58
Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
8.7K
在未经处理的裂唇和 palatal 的面整合和模块化
Sariesendy Sumardi1, Anne Marie Kuijpers-Jagtman2,3,4, Benny S Latief5
1Department of Orthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
Clinical oral investigations
|March 31, 2025
概括
未经治疗的口面裂显著改变了面组织,影响了成年人的头骨底部,大和下的整合和模块化. 这凸显了个性化治疗策略的必要性.
科学领域:
- 面生物学 面生物学
- 发育生物学是发展生物学.
- 几何形态仪表的几何形态仪表.
背景情况:
- 面部或面部裂代表了影响面部发育的常见先天性异常.
- 了解未经手术的个体的面变异,整合和模块化对于理解发育过程和规划干预至关重要.
研究的目的:
- 与未经手术的单侧裂唇和膜 (UCLA) 和单侧裂唇,膜和膜 (UCLAP) 的成年人相比,与未受影响的对照人群 (NORM) 量化面变异,整合和模块化.
主要方法:
- 在295个成年原马来人个体 (243个裂,50个对照) 的侧面头像图上利用几何形态测量.
- 分析了14个头脑测量地标,以评估面形状变异性 (PCA),群体差异 (CVA),集成和模块化,使用RV系数和协差比率.
主要成果:
- 面形状的变化主要是由垂直和斜面关系驱动的 (PC1-PC6解释了72%).
- 在UCLA,UCLAP和NORM组中观察到形状的显著差异,NORM和UCLAP之间的距离最大.
- 受裂纹影响的个体表现出明显的前后模块,与对照组的模块化组织 (头骨底部,大,下) 不同.
结论:
- 未经手术的单边UCLA和UCLAP显著影响面整合和模块化.
- 考虑先天性面组织的个性化治疗方法对于优化功能和美学结果至关重要.
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