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依赖USP14的IGF1R通过对BAP1进行上调来加剧高葡萄糖诱导的糖尿病视网膜病变

Li Yu1, Xia Zheng1, Yan Wu2

  • 1Department of Ophthalmology, Jiangxia District, The First People's Hospital of , No.1 Zhifang Cultural Avenue, Jiangxia District, Wuhan City, 430200, Hubei Province, China.

Applied biochemistry and biotechnology
|March 31, 2025
PubMed
概括

糖尿病视网膜病变 (DR) 的高葡萄糖水平通过USP14稳定增加胰岛素样生长因子1受体 (IGF1R). 抑制IGF1R或USP14可以防止DR相关的细胞损伤和铁亡.

关键词:
在 BAP1 中, BAP1 是 BAP1 的第一个类型.糖尿病视网膜病变 - 糖尿病视网膜病变铁化是铁化的一种.在IGF1R中,IGF1R是最重要的.美国 14 美元

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