相关实验视频

Updated: May 16, 2025

Using High Content Imaging to Quantify Target Engagement in Adherent Cells
07:23

Using High Content Imaging to Quantify Target Engagement in Adherent Cells

Published on: November 29, 2018

8.5K

点击化学对目标参与度研究的研究

Silvia Castelli1, Sonia Troiani2, Ulisse Cucchi2

  • 1Nerviano Medical Sciences srl, Nerviano, Milan, Italy. silvia.castelli@nervianoms.com.

Methods in molecular biology (Clifton, N.J.)
|March 31, 2025
PubMed
概括

这项研究优化了一种点击化学化学蛋白质化学方法,以识别和量化对共价小分子抑制剂的目标参与. 这种方法在细胞系统中使用布鲁顿的氨酸激酶 (BTK) 抑制剂易布鲁丁尼布进行了验证.

关键词:
化学蛋白质组是如何形成的点击"化学"就可以了.协同抑制剂 协同抑制剂基于凝的分析分析目标参与度 目标参与度

更多相关视频

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling10:49

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

Published on: September 20, 2016

12.5K
Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry07:17

Measuring Proliferation of Vascular Smooth Muscle Cells Using Click Chemistry

Published on: October 30, 2019

6.7K

相关概念视频

Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
7.8K