Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Two new species of Myxodavisia (Myxosporea: Sinuolineidae) from the gallbladder of two marine fishes from the South China Sea.

Acta tropica·2026
Same author

γ-shielding performance and irradiation-induced changes of CeO<sub>2</sub>-barite concrete.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2026
Same author

Complementary mNGS and traditional testing for bloodstream infections.

Open medicine (Warsaw, Poland)·2026
Same author

Adaptive Protein Corona Nanoassemblies Couple Cytokine Signaling with Endogenous Antigen Transport for Systemic Cancer Immunity.

Journal of the American Chemical Society·2026
Same author

Comparison of Endoscopic Cap External Snare Resection (ECESR) and Endoscopic Muscularis Dissection (EMD) for Small Gastric Submucosal Tumors (≤ 12 mm) Emerging from the Muscularis propria.

Digestive diseases and sciences·2026
Same author

Safety of hepatitis E vaccine in pregnancy.

Virology journal·2026

相关实验视频

Updated: Jun 24, 2026

Visual Detection of Multiple Nucleic Acids in a Capillary Array
08:56

Visual Detection of Multiple Nucleic Acids in a Capillary Array

Published on: November 15, 2017

7.2K

深度学习增强的手动驱动微流体芯片用于基于RPA/CRISPR的多重核酸检测.

Tao Xu1,2, Ying Zhang2, Shunji Li2

  • 1College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 31, 2025
PubMed
概括

一个新的便携式系统,R-CHIP,使用复合酶聚合酶放大和CRISPR.使高风险人乳头瘤病毒 (HR-HPV) 的快速,可访问的检测. 这项技术有助于在资源有限的环境中早期查宫癌.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?人工智能的人工智能是人工智能.社区查社区查这是一种手动驱动的微流体.高风险的人类乳头瘤病毒

更多相关视频

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
04:17

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning

Published on: May 10, 2024

564
Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
10:16

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Published on: August 16, 2024

989

相关实验视频

Last Updated: Jun 24, 2026

Visual Detection of Multiple Nucleic Acids in a Capillary Array
08:56

Visual Detection of Multiple Nucleic Acids in a Capillary Array

Published on: November 15, 2017

7.2K
DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
04:17

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning

Published on: May 10, 2024

564
Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases
10:16

Author Spotlight: Development of Simplified CRISPR-Based Tests for Rapid Detection of Infectious Diseases

Published on: August 16, 2024

989

科学领域:

  • 生物技术是生物技术.
  • 分子诊断学 分子诊断
  • 公共卫生 公共卫生

背景情况:

  • 早期发现高危人乳头瘤病毒 (HR-HPV) 对宫癌的预后至关重要.
  • 目前基于PCR的方法缺乏可访问性,阻碍了资源有限的地区的查,并导致高死亡率.

研究的目的:

  • 开发一个便携式,用户友好的系统,用于多重HR-HPV核酸检测.
  • 提高宫癌查的可访问性和效率,特别是在服务不足的地区.

主要方法:

  • 整合复合酶聚合酶放大 (RPA),CRISPR检测,手动驱动的微流体和人工智能平台 (R-CHIP).
  • 使用智能手机微图像系统与ResNet-18深度学习模型进行自动结果读取.
  • 优化为高灵敏度 (HPV-16 的 10^-17 M,HPV-18 的 10^-18 M) 和准确度.

主要成果:

  • 通过简单的手动操作,R-CHIP在不到一个小时内提供结果.
  • 在300个临床样本测试中,HPV-16和HPV-18的准确度超过95%.
  • 基于智能手机的AI读数显示,HPV-16的初始预测准确率为96.0%,HPV-18的初始预测准确率为98.0%.

结论:

  • R-CHIP是一个敏感,准确和可访问的平台,用于社区层面的HR-HPV查.
  • 该系统在资源有限的环境中对早期宫癌检测和预防具有重大潜力.
  • 综合方法为开发其他疾病的类似诊断工具提供了一个模型.