美国护士职业接触消毒剂和发生心血管疾病的风险:护士健康研究II
Yi-Xin Wang1,2, Orianne Dumas3, Raphaëlle Varraso3
1Department of Environmental Health, Shanghai Jiao Tong University, Shanghai, China.
Environmental health perspectives
|March 31, 2025
概括
护士的职业消毒剂暴露与心血管疾病 (CVD) 风险增加有关,包括心脏病和中风. 手术室护士和经常使用消毒剂的人面临的风险最高.
科学领域:
- 环境健康 环境健康
- 职业健康 职业健康 职业健康
- 心血管流行病学心血管流行病学
背景情况:
- 毒理学研究表明,接触化学消毒剂可能会导致血管功能障碍.
- 职业消毒剂使用与临床心血管疾病 (CVD) 风险之间的联系尚未得到充分证实.
研究的目的:
- 研究职业消毒剂暴露与美国护士患心血管疾病的风险之间的关联.
- 量化与特定职位角色和护理中的消毒剂暴露水平相关的CVD风险.
主要方法:
- 分析了来自护士健康研究II的75,675名护士队列,其中包括职业消毒剂暴露数据.
- 考克斯比例危险模型用于估计发生心血管疾病,冠心病 (CHD) 和中风的危险比率 (HR).
- 一个工作-任务-暴露矩阵评估了基于清洁频率和暴露于七种特定消毒剂的CVD风险.
主要成果:
- 与教师/管理人员相比,在手术室工作的护士患心血管疾病的风险增加了1.72倍.
- 每周使用消毒剂与心血管疾病风险的适度增加有关 (HR:1.22).
- 在使用喷雾/气溶消毒剂频繁或暴露于高水平特定化学物质的护士中,观察到心血管疾病风险最高.
结论:
- 在医疗保健机构中对消毒剂的职业暴露与护士患心血管疾病 (包括心血管疾病和中风) 的风险增加有关.
- 特定的工作角色 (例如,手术室) 和经常使用消毒剂有助于增加心血管风险.
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