最近的发展和磁共振成像和计算机断层扫描对比媒体的未来前景
Thomas Frenzel1, Thomas Wels, Hubertus Pietsch
1From the Bayer AG, Radiology, Berlin, Germany (T.F., H.P., L.S., J.E.); Wels - Omnino Medico, Rotkreuz, Switzerland (T.W.); Bayer U.S. LLC, Indianola, PA (P.S.); and Department of Gynecology, Obstetrics and Reproductive Medicine, University Medical School of Saarland, Homburg/Saar, Germany (J.E.).
Investigative radiology
|March 31, 2025
概括
本综述检查了新的计算机断层扫描 (CT) 和磁共振成像 (MRI) 对比剂,重点关注安全性和临床疗效. 它强调了剂,加多基剂和新兴成像技术的进步.
科学领域:
- 放射学和医学成像学 医学成像学
- 对比剂的药理学 对比剂的药理学
背景情况:
- 对比介质对于CT和MRI诊断成像至关重要.
- 持续的开发旨在提高疗效和安全性.
研究的目的:
- 审查CT和MRI对比介质的最新进展.
- 批判性地评估当前的趋势和未来的方向,与代理商的发展形成对比.
- 评估新的对比剂的临床疗效和安全性.
主要方法:
- 在过去5-8年中,对CT和MRI对比介质的进展进行了全面的文献综述.
- 对临床疗效和安全数据的分析.
- 专注于特定的药剂类型,包括含,基于加多,氧化铁和基于的药剂.
主要成果:
- 图像扫描:含的对比剂的一般安全性,对/甲状腺功能的影响,对比增强的乳房扫描和光子计数CT前景.
- 核磁共振:安全性更新,原性系统性纤维化,大脑加多沉积,以及新的高放松性药物 (加多皮克伦醇,加多夸特兰).
- 新兴药物包括向的GBCA,SPION,基于的药物和淋巴细胞成像.
结论:
- 最近的进展为CT和MRI对比介质提供了改进的诊断能力和安全配置文件.
- 新的药物和技术,如光子计数CT和淋巴成像显示显著的希望.
- 目前正在进行的研究重点是针对性交付,增强放松性和了解长期安全性.
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