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Updated: May 16, 2025

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基于水性环境中的药物-聚合物相互作用的无形固体分散物的配方设计规则的审查

Gayathri Ramachandran1, Indhu Annie Chacko1, M G Mishara1

  • 1Molecular Pharmaceutics and Biopharmaceutics Research Lab (MPBRL), Dept. of Pharmaceutics, Amrita School of Pharmacy, AIMS Health Science Campus, Amrita Vishwa Vidyapeetham, Ponekkara, Kochi 682041, India.

International journal of pharmaceutics
|March 31, 2025
PubMed
概括

无形固体分散 (ASDs) 提高了药物的溶解性和生物可用性. 了解药物聚合物相互作用 (DPI) 对于稳定超和和优化ASD配方设计至关重要.

关键词:
无形固体分散的分散.增强生物可用性增强生物可用性溶解机制 溶解机制 溶解机制药物聚合物相互作用 药物聚合物相互作用阶段行为 阶段行为超和稳定性 超和稳定性

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