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Updated: May 16, 2025

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卡塔兰丁酸盐通过破坏HIF-1α的稳定性来改善骨质细胞形成

Luqiong Cai1, Chenxin Yu1, Binli Zhao1

  • 1Department of Endocrinology, The 2(nd) Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China; The 2(nd) School of Medicine, Wenzhou Medical University, Wenzhou, China.

Cellular signalling
|March 31, 2025
PubMed
概括

卡塔兰丁酸盐 (CAT) 在治疗绝经后骨质疏松症 (PMOP) 中表现有前途. 它通过降解HIF-1α抑制骨质细胞活性,在临床前模型中改善骨密度和结构.

关键词:
低氧诱导因子-1α.骨质细胞生成 (Osteoclastogenesis) 是一个过程.氧化应激是一种氧化应激.绝经后的骨质疏松症 绝经后的骨质疏松症兰克尔 (Rankl) 是一个名字.

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