增加临床招聘率到单个地点的观察性研究:质量改善研究
Hayley Macleod1,2, Nadine Copty3, Damien Doherty4
1UCD Conway SPHERE Research Group, Conway Institute, University College Dublin, Dublin, Ireland.
BMJ open quality
|March 31, 2025
概括
改善临床试验招聘需要加强沟通和高效的流程. 这项质量改进研究通过实施有针对性的沟通和流程优化策略,成功地将癌症相关血栓瘤的患者入学率提高了一倍.
科学领域:
- 临床研究行动临床研究行动.
- 质量改进方法的方法.
- 患者招募策略 患者招募策略
背景情况:
- 临床招聘是多学科研究的一个主要挑战,往往推迟研究完成.
- 缓慢的患者入学率需要创新的解决方案来提高效率.
- 临床部门内部加强沟通对于成功招聘临床试验人员至关重要.
研究的目的:
- 在Mater Misericordiae大学医院 (MMUH) 实施质量改善 (QI) 研究.
- 增加癌症相关血栓瘤患者进入EXPECT研究的缓慢招募率.
- 确定和实施有效的策略,以加强临床试验招聘.
主要方法:
- 使用过程和利益相关者映射与计划-做-研究-行动 (PDSA) 周期一起.
- PDSA第1周期的重点是通过临床项目赞助商和宣传举措加强临床沟通和研究教育.
- PDSA Cycle 2集中于通过每周的QI会议和专门的QI团队来提高流程效率和配对样本采集.
主要成果:
- 第一个PDSA周期的倡议增加了每月从一到两名患者的招聘.
- 与初始阶段相比,QI研究期间的患者入学量几乎翻了一番.
- 在实施工艺效率措施后,对联样本采集率在统计学上显著增加了三倍 (20%至66%).
结论:
- 一个高度参与的研究团队,特别是临床项目赞助商,对于推动招聘至关重要.
- 有效的招聘流程对于克服招生瓶至关重要.
- 质量改善举措可以显著提高临床试验招聘率和效率.
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