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希格拉效应剂IpaH1.4颠覆宿主E3结合酶RNF213,以逃避抗菌免疫

Xindi Zhou1, Huijing Zhang1,2, Yaru Wang1,3

  • 1State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200032, China.

Nature communications
|March 31, 2025
PubMed
概括

希格拉柔性菌通过降解抗菌蛋白RNF213使用其效应器IpaH1.4.4来逃避宿主免疫力. 这种细菌策略在感染期间促进病原体的增殖.

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