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Updated: May 16, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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铁和STING-type-I干扰素通路之间的相互调节通过树突细胞成熟抑制了头部和部状细胞癌的生长

Mingyu Li1,2,3, Shufang Jin2,3,4, Hailong Ma5,6,7

  • 1Department of Oral Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, No. 639, Zhizaoju Rd, Shanghai, 200011, China.

Oncogene
|March 31, 2025
PubMed
概括

头癌中的铁灭通过激活STING-IFN-I通路来抑制瘤,增强树突细胞成熟. 将铁灭菌诱导剂与STING激动剂结合起来,为HNSCC提供了一个有前途的治疗策略.

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