相关实验视频
Updated: May 12, 2026

14:40
Long-term Lethal Toxicity Test with the Crustacean Artemia franciscana
Published on: April 14, 2012
19.5K
在彩虹鱼幼中具有致命和次致命毒性
Joëlle Auclair1, Eva Roubeau-Dumont1, Chantale André1
1Aquatic Contaminants Research Division, Environnement and Climate Change Canada, 105 McGill, Montréal, Québec, H2Y 2E7, Canada.
Environmental science and pollution research international
|March 31, 2025
概括
沉重的稀土元素 (Yb) 对未成年彩虹有毒. 在低至60μg/L的度下观察到致命效应,影响生物标志物和鱼类存活率.
科学领域:
- 环境毒理学环境毒理学
- 生态毒理学 生态毒理学
- 重金属污染 污染重金属污染
背景情况:
- 由于固体废物处置,城市废水中越来越多地发现重稀土元素,如 (Yb).
- 了解Yb对水生生态系统的环境影响至关重要.
研究的目的:
- 为了确定 (Yb) 对未成年彩虹鱼的致命和次致命毒性.
- 为了确定特定的生物标志物,表明Yb暴露和压力.
主要方法:
- 彩虹鱼幼在15°C下96小时暴露在不同度的Yb3+ (0.0640毫克/升) 中.
- 死亡率被记录下来,生物标志物包括蛋白质聚合,氨酸,脂质过氧化 (LPO) 和DNA损伤在和肝脏中被分析.
主要成果:
- 对Yb的96小时致命度 (LC50) 确定为2.7 ± 0.66 mg/L.
- 在明显低于LC50的度下观察到亚致命效应,一些生物标志物在45倍低的水平上作出反应.
- 肝脏氨酸,状DNA链断裂,LPO和肝脏蛋白质聚合与鱼类的生存有积极的相关性.
结论:
- 伊特 (Yb) 对未成年彩虹鱼具有显著的毒性.
- 暴露96小时后,低至60μg/L的度可能会产生潜致死效应.
- 这种度是评估Yb污染水域水生动物健康的关键值.
相关概念视频
Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Derivatives: Problem Solving
Temperature-Dependent Growth of Brook TroutThe growth of brook trout is closely influenced by water temperature. Experimental data demonstrate how trout weight changes over a 24-day period in response to varying water temperatures. At lower temperatures, such as 15.5 degrees Celsius, brook trout show significant weight gain. However, as the temperature increases, the amount of weight gained steadily decreases. At the highest temperature measured, 24.4 degrees Celsius, trout experience a net...

