为COVID-19隔离住院的老年患者的食和吞功能的变化:回顾性队列研究
Kenya Hamazaki1,2, Toru Morikawa2,3, Mari Nezu2
1Department of General Internal Medicine, Kobe City Medical Center West Hospital, Kobe, Japan.
Journal of general internal medicine
|March 31, 2025
概括
经历隔离的COVID-19的老年患者面临减少口服摄入量. 较低的疾病前口服功能显著增加了衰退的风险和更高的出院后死亡率.
科学领域:
- 老年学是一门学科.
- 传染性疾病 传染性疾病
- 临床营养学 临床营养学
背景情况:
- COVID-19隔离扰乱了基本护理,包括老年患者的口服摄入支持.
- 了解对食和吞的影响对于这个脆弱的人群至关重要.
研究的目的:
- 在老年患者的COVID-19住院期间评估口服功能的变化 (功能性口服摄入量表 - FOIS).
- 确定这些变化与出院后180天死亡率之间的关联.
主要方法:
- 一项回顾性队列研究包括337名因COVID-19住院的老年患者 (≥65岁).
- 功能性口服摄入量表 (FOIS) 在疾病发病前和出院时进行测量.
- 死亡率在发病后的180天内被评估,住院死亡率被认为是FOIS降低4级.
主要成果:
- 较低的基线FOIS (FOIS前) 与住院期间FOIS的较大下降显著相关.
- 2级FOIS降低与27.9%的180天死亡率相关,而3级降低与46.0%的死亡率相关.
- 在FOIS前的水平中,COVID-19的严重程度是相似的,这表明基线功能是关键因素.
结论:
- 住院前口服摄入状态是老年COVID-19患者吞功能下降的重要预测因素.
- 住院期间FOIS下降的程度与180天死亡风险的增加密切相关.
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