散发性静脉瘤的潜在症状变化:观察,微手术和放射性手术的比较
Karl R Khandalavala1, Christine M Lohse2, Nicole M Tombers1
1Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic.
概括
放射性外科手术加剧了前庭神经瘤 (VS) 患者的耳声严重程度,与观察或微手术不同. 对于VS的治疗决策应该考虑主观症状变化,而不是仅仅依赖症状得分.
科学领域:
- 神经外科 神经外科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
背景情况:
- 垂体神经瘤 (VS) 是一种影响听觉和垂体神经的瘤.
- 患者报告的结果对于评估VS管理的有效性至关重要.
研究的目的:
- 为了比较患者报告的症状严重性得分在观察,微手术和放射手术中,用于零星的VS.
- 根据VS治疗来确定耳,头/失衡和头痛严重程度的差异.
主要方法:
- 在455名成年患者中进行了前性的纵向调查,这些患者有偶发性VS.
- 症状 (耳,头,头痛) 在10分级别上得分.
- 从临床上重要的变化定义为与基线的2分差.
主要成果:
- 在放射性手术 (+0.8分) 后,声严重程度得分显著增加,但在观察或微手术后没有显著增加.
- 与观察和微手术相比,较少的患者经历了放射性手术的临床重要耳声改善.
- 两组之间没有观察到头/失衡或头痛严重程度变化的显著差异.
结论:
- 放射性外科手术与恶化耳声和较少的改善有关,与零星VS的观察和微手术相比.
- 对VS的管理决策应将主观症状变化与其他临床因素整合起来.
- 治疗对患者报告的症状的影响的变化需要对VS管理采取全面的方法.
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