抑郁症与心脏的联系:从NHANES 2005-2018癌症患者的心血管风险
Zheling Chen1,2, Xiuxiu Qiu3, Hao Chi4
1Cardiovascular Department, ShuGuang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
BMC psychiatry
|April 1, 2025
概括
抑郁症增加了癌症患者心血管疾病 (CVD) 的风险. 严重的抑郁症显著提高了心血管疾病的几率,强调了在癌症治疗中需要综合心理健康监测的必要性.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
背景情况:
- 抑郁症是一般人群中心血管疾病 (CVD) 的已知危险因素.
- 癌症患者中抑郁症和心血管疾病风险之间的关联仍然不太清楚.
研究的目的:
- 研究美国癌症患者抑郁症状与心血管疾病发病风险之间的关系.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) (2005-2018) 的数据.
- 包括1890名癌症患者,通过患者健康问卷-9 (PHQ-9) 评估抑郁症状.
- 使用加权多变量逻辑回归和子组分析来评估心脏病风险关联.
主要成果:
- 在抑郁症严重程度和心血管疾病风险之间发现了显著的关联.
- 在PHQ-9得分的每一个单位增加与心血管疾病的1.09增加的几率相关 (AOR=1.09,95% CI:1.05-1.14).
- 重度抑郁明显增加了心血管疾病的几率 (AOR=6.82,95% CI:2.39-19.50),显示出分级的,线性剂量反应关系.
结论:
- 抑郁症严重程度增加与癌症患者心血管疾病发病率较高有关.
- 监测抑郁症状对于综合护理和管理心血管风险至关重要.
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