对牙周炎和炎症性肠道疾病之间的关联进行系统审查和网络元分析
Ariyan Ayati1, Sajad Khodabandelu2, Sara Khaleghi2
1School of Medicine, Shahid Beheshti University of Medical Sciences, Postal code, Tehran, 19839-63113, Iran.
BMC oral health
|April 1, 2025
概括
炎症性肠病 (IBD),包括性结肠炎 (UC) 和克罗恩氏病.
科学领域:
- 胃肠道学和口腔健康
- 流行病学 流行病学
- 系统性炎症性疾病系统性炎症性疾病
背景情况:
- 炎症性肠病 (IBD),包括性结肠炎 (UC) 和克罗恩病 (CD),与牙周病 (PD) 的风险增加有关.
- 了解IBD亚型和牙周炎之间的特定关系对于患者管理至关重要.
研究的目的:
- 评估牙周炎和IBD的亚型 (UC和CD) 之间的关联.
主要方法:
- 在主要数据库 (Web of Science,PubMed,Google Scholar,Scopus) 进行了系统的文献搜索,截至2024年2月.
- 研究根据PRISMA指南进行选,不包括案例系列,评论和动物研究.
- 使用R软件对13项涉及9134名患者的研究进行了元分析,并根据JBI标准评估了偏差风险.
主要成果:
- 在患有IBD (UC和CD) 的患者中,牙周炎的患病率显著更高.
- 在克罗恩病 (OR:4.30) 和性结肠炎 (OR:4.55) 中观察到高牙周炎发病率.
- 在CD和UC患者之间没有发现牙周炎风险的显著差异 (OR:0.96).
结论:
- 患有UC和CD的患者患有牙周炎的可能性更高.
- 牙周炎的患病率在UC和CD患者之间是相似的.
- 建议对IBD患者进行牙周炎的例行查,原因是增加了IBD的风险和对生活质量的潜在影响.
相关概念视频
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