空气污染和皮肤疾病
Hye Sung Han1,2, Joon Seok3, Kui Young Park4
1Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
Annals of dermatology
|April 1, 2025
概括
空气污染会损害皮肤健康,造成氧化应激和炎症,恶化和湿疹等疾病. 通过抗氧化和抗炎治疗来保护皮肤屏障可以帮助减轻这些影响.
科学领域:
- 环境皮肤病学环境皮肤病学
- 毒理学 毒理学 毒理学
背景情况:
- 空气污染对全球健康构成重大风险.
- 流行病学数据将空气污染物与炎症性皮肤疾病 (皮炎,牛皮,),加速皮肤衰老,脱发和皮肤癌联系起来.
研究的目的:
- 审查空气污染对皮肤健康的影响.
- 阐明潜在的机制,并讨论治疗/化品干预措施.
主要方法:
- 流行病学研究和机械学研究的文献综述.
- 分析反应性氧物种,氧化应激和基碳化合物受体信号传递的作用.
- 检查皮肤屏障破坏和炎症途径.
主要成果:
- 空气污染物诱导反应性氧物种,导致氧化应激.
- 基碳化合物受体通路调解污染物对皮肤的影响.
- 空气污染物损害皮肤屏障功能,促进炎症.
结论:
- 抗氧化剂和抗炎疗法至关重要.
- 恢复皮肤屏障功能是减轻污染对皮肤不利影响的关键.
- 有针对性的干预措施可以保护皮肤健康免受环境污染的影响.
相关概念视频
Skin Diseases and Disorders
2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Other Pulmonary Disorders
786
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
786
Types of Toxins
1.6K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.6K
Assessment of Airway, Skin Color, and Use of Accessory Muscles
937
A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
Introduction
The initial evaluation of a patient's respiratory system...
937


