身体活动与2型糖尿病之间的非线性关联在240万韩国人口中,2009-2022年:全国代表性研究
Wonwoo Jang1,2, Seokjun Kim1,2, Yejun Son2,3
1Department of Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
Journal of Korean medical science
|April 1, 2025
概括
更高的体力活动并不总是降低2型糖尿病的风险,显示出非线性关系. 建议将中等强度PA (MPA) 和强烈强度PA (VPA) 结合起来,以获得最佳的健康益处.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 运动科学 运动科学
背景情况:
- 过度体力活动 (PA) 可能不会带来额外的健康益处.
- 关于PA和2型糖尿病之间的剂量反应关系的定量数据有限.
- 本研究通过检查PA强度,频率和MET得分与2型糖尿病患病率相关的差距来解决这一问题.
研究的目的:
- 为了研究体力活动 (PA) 和2型糖尿病患病率之间的剂量反应关系.
- 分析PA强度 (MET评分),频率和类型与糖尿病风险的关联.
- 在大量人群中确定最佳的PA策略来预防2型糖尿病.
主要方法:
- 韩国社区健康调查的2,428,448名参与者的全国横截面分析.
- 权重通用添加模型用于评估MET得分和2型糖尿病几率比率 (ORs) 之间的非线性关联.
- 分类分析检查了中等强度PA (MPA) 和强烈强度PA (VPA) 的联合关联,以及PA频率.
主要成果:
- 在MET得分和糖尿病患病率之间发现了非线性关联,ORs增加超过1,028MET-min/week.
- 同时使用MPA (300-600MET-min/周) 和VPA (>600MET-min/周) 观察到最低的OR (0.79).
- 无论是"周末战士"还是"经常活跃"的人,都比不活跃的人有较低的OR,活跃组之间没有显著差异.
结论:
- 身体活动与2型糖尿病患病率的关联是非线性的,不总是随着PA水平的提高而下降.
- 推适量强度PA (MPA) 和强度PA (VPA) 的适当组合用于预防2型糖尿病.
- 在这个大规模的韩国样本中,PA频率对2型糖尿病患病率没有显著影响.
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