在韩国患有骨关节炎的患者中使用心理药物
Seong-Hun Kang1, Hyun Ah Kim2, Insun Choi3
1Division of Rheumatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Journal of Korean medical science
|April 1, 2025
概括
许多患有骨关节炎 (OA) 的老年人被处方精神药物,即使没有明确的医疗需要. 阿片类药物和二二类药物的使用减少,但其他精神药物处方增加,引发了安全问题.
科学领域:
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 骨关节炎 (OA) 疼痛管理仍然具有挑战性,导致全球非标签性精神药物处方增加.
- 这项研究调查了韩国OA患者使用心理药物的趋势.
研究的目的:
- 分析2011年至2020年间被诊断患有关节或膝关节骨关节炎的患者的精神药物处方模式的变化.
- 确定特定的药物类别及其在这个患者群体中的使用趋势.
主要方法:
- 利用韩国国家医疗保险服务数据集,包括1,821,158名65岁以上的OA患者.
- 对各种精神药物类别的处方率 (流行率和长期使用) 进行了检查,包括阿片类药物,类药物,抗药和抗抑郁药.
- 基于精神病并发症的存在或不存在的分层分析.
主要成果:
- 总体而言,在2018年,精神药物处方率略有下降,从58.2%降至52.0%,然后稳定下来. 长期处方率在2018年之后略有增加.
- 阿片类药物和长效二二类药物的处方减少. 然而,在患有精神病并发症的患者中,抗药和血清素 - 上腺素再吸收抑制剂 (SNRIs) 的处方增加了.
- 对于没有精神病并发症的患者,抗药,选择性血清素再吸收抑制剂 (SSRI),其他抗抑郁药和非典型抗精神病药物的处方显示有所增加. 通常处方的药物包括迪亚泽帕姆和阿尔普拉佐拉姆.
结论:
- 韩国老年有OA的成年人中有很大一部分接受精神药物治疗,而没有明确的症状说明他们的情况.
- 该研究强调了对OA疼痛有效性有限的药物的使用以及老年人群中潜在的安全问题.
- 处方趋势表明,即使没有确诊的精神疾病,也会转向某些抗抑郁药和抗精神病药.
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