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Updated: May 16, 2025

The use of SC1 Pluripotin to Support mESC Self-renewal in the Absence of LIF
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The use of SC1 Pluripotin to Support mESC Self-renewal in the Absence of LIF

Published on: November 18, 2009

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异质的Sox2转录动态介导mESC中的多能性维护,以应对LIF信号干扰

Gaochen Jin, Emilia A Leyes Porello, Jingchao Zhang

    bioRxiv : the preprint server for biology
    |April 1, 2025
    PubMed
    概括

    破坏LIF信号减少了小鼠胚胎干细胞 (mESCs) 中的Sox2基因活动,通过改变转录爆发. 这种减少,而不是完全的损失,触发了多能性损失,并揭示了Sox2.

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    Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal08:01

    Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

    Published on: May 30, 2012

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