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Updated: May 16, 2025

Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs
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Biotin-based Pulldown Assay to Validate mRNA Targets of Cellular miRNAs

Published on: June 12, 2018

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一个统一的模型,用于微RNA引导的信使RNAs的沉默

Tanmay Chatterjee1, Shankar Mandal1, Sujay Ray1

  • 1Single Molecule Analysis Group and Center for RNA Biomedicine, Department of Chemistry, University of Michigan, Ann Arbor, Michigan, 48109, United States.

bioRxiv : the preprint server for biology
|April 1, 2025
PubMed
概括

RNA沉默依赖于miRNA引导的RNA诱导沉默复合体 (miRISC) 结合的mRNA. 新的研究表明,miRISC采用了不同的状态,为目标识别偏爱5'种子或3'非种子配对.

关键词:
在2年前的时间里.在RNA诱导的沉默复杂的沉默复杂.构造动力学 构造动力学动力指纹的指纹.这是一个微型RNA.单个分子光的光.目标识别 目标识别

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