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Updated: May 16, 2025

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae
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SEL1L-HRD1 ER相关的降解促进了前激素转化酶2的成熟和岛屿α细胞中的葡萄糖生成

Wenzhen Zhu1, Linxiu Pan1,2, Xianwei Cui3

  • 1Division of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.

bioRxiv : the preprint server for biology
|April 1, 2025
PubMed
概括

细胞内膜网关联降解 (ERAD) 调节了前激素转化酶2 (PC2) 的成熟,这对岛屿α细胞中葡萄糖的产生至关重要. 这种蛋白质质量控制途径对于维持正常的葡萄糖分和α细胞功能至关重要.

关键词:
在这里,你会看到一个很棒的景点.在PC2中,PC2是PC2.在SEL1L-HRD1 ERADAD中.葡萄糖是一种葡萄糖.在proPC2中使用 proPC2.葡萄糖前 (Proglucagon) 是一种蛋白质降解 蛋白质降解蛋白质折叠 蛋白质的折叠

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