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Updated: May 16, 2025

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
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甲基醇通过Rev1相关的滑动和错配变异单链DNA

Sriram Vijayraghavan, Alessandra Ruggiero, Samuel Becker

    bioRxiv : the preprint server for biology
    |April 1, 2025
    PubMed
    概括

    甲基醇 (MG) 是一种反应性化物,通过破坏单链DNA,导致酵母中的DNA突变. 这种与癌症相关的突变性过程依赖于特定的DNA修复途径,并且当排毒受损时会升高.

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