相关实验视频

Updated: Jun 16, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 29, 2010

注册报告:复制和扩展的复制和扩展

Karli M Nave, Erin E Hannon, Joel S Snyder

    bioRxiv : the preprint server for biology
    |April 1, 2025
    PubMed
    概括

    复制研究发现,想象音乐节拍的神经效应比之前报道的要小. 这表明需要大样本大小才能使用频率标记可靠地检测节拍感知.

    关键词:
    听觉神经科学 听觉神经科学节拍和计时器的感知.频率标记的标记是一个频率标记.多个实验室的多个实验室音乐认知 音乐认知预注册 预注册 预注册 预注册复制复制复制复制复制复制复制

    更多相关视频

    Massively Parallel Reporter Assays in Cultured Mammalian Cells11:03

    Massively Parallel Reporter Assays in Cultured Mammalian Cells

    Published on: August 17, 2014

    G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome06:40

    G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

    Published on: March 22, 2018

    相关概念视频

    DNA Replication02:40

    DNA Replication

    DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
    Replication in Prokaryotes
    DNA replication...
    48.0K
    The DNA Replication Fork01:02

    The DNA Replication Fork

    An organism’s genome needs to be duplicated in an efficient and error-free manner for its growth and survival. The replication fork is a Y-shaped active region where two strands of DNA are separated and replicated continuously. The coupling of DNA unzipping and complementary strand synthesis is a characteristic feature of a replication fork.   Organisms with small circular DNA, such as E. coli, often have a single origin of replication; therefore, they have only two replication...
    35.3K
    The Replisome03:01

    The Replisome

    DNA replication is carried out by a large complex of proteins that act in a coordinated matter to achieve high-fidelity DNA replication. Together this complex is known as the DNA replication machinery or the replisome.
    The synthesis of the leading and lagging strands is a highly coordinated process. To explain this, the “Trombone model” was proposed by Bruce Alberts in 1980. The DNA loop formation starts when a primer is synthesized on the parent lagging strand. The loop grows with...
    32.7K
    Restarting Stalled Replication Forks02:37

    Restarting Stalled Replication Forks

    DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart,...
    5.7K
    Replication in Prokaryotes01:32

    Replication in Prokaryotes

    DNA replication has three main steps: initiation, elongation, and termination. Replication in prokaryotes begins when initiator proteins bind to the single origin of replication (ori) on the cell's circular chromosome. Replication then proceeds around the entire circle of the chromosome in each direction from the two replication forks, resulting in two DNA molecules.
    Many Proteins Work Together to Replicate the Chromosome
    Replication is coordinated and carried out by a host of specialized...
    23.9K
    Replication in Eukaryotes01:29

    Replication in Eukaryotes

    In eukaryotic cells, DNA replication is highly conserved and tightly regulated. Multiple linear chromosomes must be duplicated with high fidelity before cell division, so there are many proteins that fulfill specialized roles in the replication process. Replication occurs in three phases: initiation, elongation, and termination, and ends with two complete sets of chromosomes in the nucleus.
    Many Proteins Orchestrate Replication at the Origin
    Eukaryotic replication follows many of the same...
    12.8K