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Updated: May 21, 2025

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
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Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

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针对脑髓母细胞瘤中Myc驱动电路的过程性转录

Lays Martin Sobral, Faye M Walker, Krishna Madhavan

    bioRxiv : the preprint server for biology
    |April 1, 2025
    PubMed
    概括

    抑制CDK9是一种有前途的新策略,用于治疗Myc增强性脑髓母细胞瘤 (Myc-MB),这是一种高风险的儿童大脑瘤. 向CDK9破坏了关键的癌症驱动程序,为表现不佳的患者提供了潜在的新疗法.

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