相关实验视频

Updated: May 16, 2025

A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis
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A11-positive β-amyloid Oligomer Preparation and Assessment Using Dot Blotting Analysis

Published on: May 22, 2018

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中基因减弱了Aβ纤维组合和粉样斑块形成

Masihuz Zaman1,2, Shu Yang1,2,3, Ya Huang1,2

  • 1Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

bioRxiv : the preprint server for biology
|April 1, 2025
PubMed
概括

在阿尔茨海默氏症模型中,Midkine (MDK) 蛋白降低了粉样β (Aβ) 组合. 失去MDK会加速粉样斑块的形成和大脑炎症,这表明MDK对阿尔茨海默病的病理有保护作用.

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Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

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相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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