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Updated: May 16, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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贝叶斯的遗传类推理确定了药物标和可重复使用的药物,用于人类复杂疾病

Noah Lorincz-Comi1,2, Feixiong Cheng1,2,3

  • 1Cleveland Clinic Genome Center, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

medRxiv : the preprint server for health sciences
|April 1, 2025
PubMed
概括

复杂的疾病具有共同的遗传因素,使得能够识别更安全的药物点. 我们的模型揭示了跨特征的共享基因架构,揭示了新的治疗机会和药物重用潜力,用于阿尔茨海默氏症和ALS等疾病.

关键词:
多基因性 多基因性复杂的疾病复杂的疾病.药物重用是为了改变药物的用途.可以使用药物的基因.基因关联测试是基因关联测试.全基因组关联研究研究.类型的类型.多基因的多基因.

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