儿童SARS-CoV-2感染以及焦虑和抑郁的发展
Frederick Dun-Dery1, Jianling Xie2, Roger Zemek3,4
1Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Frontiers in pediatrics
|April 1, 2025
概括
这项研究发现,SARS-CoV-2感染与儿童出现新的焦虑或抑郁症诊断之间没有直接联系. 然而,受感染的儿童报告了更多的症状,如混乱和失眠,突出了与大流行有关的社会影响儿童心理健康.
科学领域:
- 儿科健康 儿科健康
- 传染性疾病 传染性疾病
- 心理健康 心理健康
背景情况:
- 在SARS-CoV-2感染后的儿童中,新出现的心理健康问题需要澄清直接与间接的流行病影响.
- 在患有或没有SARS-CoV-2感染的儿童中评估新的焦虑和/或抑郁症诊断的频率至关重要.
研究的目的:
- 在儿科急诊室测试SARS-CoV-2的儿童中评估新的焦虑和/或抑郁症诊断的发生率.
- 区分直接的病毒影响和间接的流行病影响对儿科精神健康.
主要方法:
- 一项前性队列研究在14个加拿大三级护理儿科急诊部进行.
- 在2020年8月至2022年2月期间测试SARS-CoV-2的18岁以下儿童被跟踪了6个月和12个月.
- 国际严重急性呼吸道和新兴感染联盟 (ISARIC) 长期COVID儿科问卷被调整为后续评估.
主要成果:
- 在SARS-CoV-2-阳性 (4.1%) 和SARS-CoV-2-阴性 (2.8%) 儿童之间没有观察到新的焦虑和/或抑郁症诊断的显著差异.
- 在12岁以上的SARS-CoV-2-阴性儿童中,与12岁以下的儿童相比,新的焦虑/抑郁症诊断的患病率更高.
- 感染SARS-CoV-2的儿童在6个月或12个月后更有可能报告混乱/缺乏集中力,腹痛和失眠.
结论:
- SARS-CoV-2 感染与儿童焦虑或抑郁症的新诊断没有直接关联.
- 在SARS-CoV-2-阳性儿童中,报告非特异性症状 (混乱,腹痛,失眠) 的增加需要进一步调查病理生理机制.
- 疫情期间的社会变化显著影响了儿童的心理健康,无论直接感染SARS-CoV-2.
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