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Updated: Jul 10, 2026

Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents
07:10

Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents

Published on: March 7, 2011

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第1阶段,首次对人类进行,单/多次上升剂量Iluzanebart在健康志愿者中的研究

Andreas Meier1, Spyros Papapetropoulos1, Andrew Marsh1

  • 1Formerly Vigil Neuroscience, Inc., Watertown, Massachusetts, USA.

Annals of clinical and translational neurology
|April 1, 2025
PubMed
概括

一种TREM2激动剂Iluzanebart在健康志愿者中显示出良好的安全性和耐受性. 这种抗体表现出良好的药理动力学和中枢神经系统暴露,支持其对神经疾病的发展.

关键词:
在CSF-1受体.在TREM2中,我们可以使用TREM2.成人发病的白细胞大脑病变,带有轴突球体和有色素的质细胞.一个错误的假象微质细胞中的微质细胞

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