关于SARS-CoV-2感染的神经表现的最新信息
Ferron F Ocampo1, Kathryn B Holroyd2
1Department of Psychiatry, University of Toronto, Toronto, Canada.
Current opinion in infectious diseases
|April 1, 2025
概括
COVID-19幸存者经常经历持续的神经问题,包括认知功能障碍和疲劳,影响结果. 目前正在研究有效的治疗方法,并了解长期的神经系统影响.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 由于COVID-19的流行,幸存者经历神经复杂症的数量显著增加.
- 神经症状可以在急性感染期间表现出来,并长期存在.
研究的目的:
- 综合有关COVID-19急性和慢性神经症状的当前知识.
- 审查现有和新兴的治疗策略,以治疗COVID-19后的神经疾病.
主要方法:
- 这是一篇综述性文章,综合了现有的文献和研究结果.
- 流行病学研究和正在进行的临床试验的分析.
主要成果:
- 在急性COVID-19期间的神经症状与较差的医院和功能结果有关.
- 常见的神经系统后果包括认知功能障碍,头痛,自主功能障碍和慢性疲劳,在各种SARS-CoV-2菌株中普遍存在.
- 新出现的证据表明,SARS-CoV-2感染与大脑结构变化之间存在联系.
结论:
- 持续的COVID-19神经表现具有显著的个人和社会影响.
- 预防和多模式治疗策略对于管理这些疾病至关重要.
- 需要进一步的研究才能充分了解长期的神经后果,包括与神经退行性疾病的潜在联系.
相关概念视频
Disorders of the Nervous Tissue
975
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises...
975
Neural Regulation
39.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.0K
Local Anesthetics: Adverse Effects
378
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
378
Parkinson's Disease: Overview
353
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
353
Negative and Cognitive Symptoms of Schizophrenia
39
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
39
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
41
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
41


