起源,分散和影响:中国和欧洲猪种群之间的双向入侵
Yibin Qiu1,2, Langqing Liu1,3, Min Huang1,2
1State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou, Guangdong, 510642, China.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|April 1, 2025
概括
中国和欧洲猪之间的双向基因流形成了现代品种. 结构变异 (SVs) 起着关键作用,其中BMP2类型与较大的体型相关,起源于古代欧洲猪.
科学领域:
- 动物遗传学动物遗传学
- 基因组学就是基因组学.
- 进化生物学 进化生物学
背景情况:
- 中国和欧洲猪种群之间的人类介导的基因流动是常见的.
- 相互的内向模式和结构变异 (SVs) 的作用尚未得到充分理解.
研究的目的:
- 描述中国和欧洲猪之间的双向侵入性.
- 调查SVs对遗传交换和特征增强的贡献.
主要方法:
- 来自418头猪的全基因组再测序数据.
- 对单核酸多态 (SNP) 和单核酸多态 (SV) 的分析.
- 使用古代猪基因组进行验证.
主要成果:
- 确定了3558个双向内向的基因组段和30个SV.
- 在SVs和SNP之间发现不完全的链接不平衡,限制了基于SNP的分析.
- 确定了与身体尺寸改善相关的BMP2单元型,可能起源于古代欧洲猪.
结论:
- 双向内向显著塑造了现代猪的遗传组成和特征.
- 在理解基因交换和表型变异方面,SVs至关重要.
- 古代基因组为进化单元类型的进化历史提供了洞察力.
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