一样但不同? :选择和碰撞器偏差对内部有效性的影响的系统审查
Natalie S Levy1,2, Katrina L Kezios1
1Department of Epidemiology, Mailman School of Public Health, Columbia University.
Epidemiology (Cambridge, Mass.)
|April 1, 2025
概括
选择偏差和碰撞器偏差在理论上是对内部有效性的类似威胁,但文献评论显示了关于它们影响的不同结论. 需要进一步研究对撞击器偏差,以更好地预测和量化其影响.
科学领域:
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 选择偏差和碰撞器偏差是已知的对观察性研究内部有效性的威胁.
- 最近的研究表明,这些偏见的概念统一,暗示对观察到的关联有类似的影响.
研究的目的:
- 在流行病学文献中系统地审查和总结有关选择偏差和碰撞器偏差影响的现有知识.
- 为了比较这些偏差是如何讨论他们的规模,方向,和受影响的层.
主要方法:
- 对内部有效性,选择偏差和碰撞器偏差 (2000-2024) 的同行评审文章和教科书进行系统搜索.
- 关于偏差大小,方向,受影响层和评估条件的结论的抽象.
- 分析了33篇文章和12本教科书.
主要成果:
- 碰撞器偏差通常被描述为最小的,而选择偏差效应则被报告为可变的.
- 大多数碰撞器偏差评估都假定了一个尖的零假设 (没有暴露结果关系).
- 选择和碰撞器偏差文献讨论了相互作用和受影响的层次的不同.
结论:
- 尽管理论上的等价性,选择和碰撞机偏差对研究结果的后果在文献中呈现不同.
- 建议对碰撞器偏差进行进一步的研究,特别是在利的零值之外,并考虑相互作用效应.
- 这些调查可能会改善对碰撞机偏差对内部有效性影响的预测和量化.
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