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Updated: May 12, 2026

Mass Spectrometric Analysis of Glycosphingolipid Antigens
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在脑脊液中分析N-甘氨酸:一种甘氨酸学方法

Cristian D Gutierrez Reyes1, Sherifdeen Onigbinde1, Joy Solomon1

  • 1Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, USA.

Methods in molecular biology (Clifton, N.J.)
|April 1, 2025
PubMed
概括

分析脑脊液 (CSF) 的N-甘氨酸对于理解神经退行性疾病至关重要. 这项研究提出了一种使用液态染色体质谱法 (LC-MS) 进行精确的糖在CSF中的分析的优化方法.

关键词:
在CSF的CSF中,这就是LC-MS.N-Glycans 是一种蛋白质.通过甲基化进行了甲基化.

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相关概念视频

Protein Glycosylation01:25

Protein Glycosylation

Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...