Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Morphogenesis02:19

Morphogenesis

23.5K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
23.5K
Gastrulation01:56

Gastrulation

55.3K
Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
55.3K
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.0K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.0K
Neurulation01:30

Neurulation

41.4K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
41.4K
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

3.1K
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
3.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A likelihood-based Bayesian inference framework for the calibration of and selection between stochastic velocity-jump models.

Journal of the Royal Society, Interface·2026
Same author

The influence of cell phenotype on collective cell invasion into the extracellular matrix.

Bulletin of mathematical biology·2025
Same author

From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms.

Development (Cambridge, England)·2025
Same author

Bayesian networks for network inference in biology.

Journal of the Royal Society, Interface·2025
Same author

Approximate Solutions of a General Stochastic Velocity-Jump Model Subject to Discrete-Time Noisy Observations.

Bulletin of mathematical biology·2025
Same author

The genome sequence of White-foot Bell moth, <i>Epiblema foenella</i> (Linnaeus, 1758).

Wellcome open research·2025
Same journal

Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys.

eLife·2026
Same journal

Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation.

eLife·2026
Same journal

Restraint of melanoma progression by cells in the local skin environment.

eLife·2026
Same journal

Brawn before bite in endemic Asian eutherian mammals after the end-Cretaceous extinction.

eLife·2026
Same journal

Experimental evolution to thermal stress indicates climate resilience in a cosmopolitan arthropod.

eLife·2026
Same journal

Correlates of protection against African swine fever virus identified by a systems immunology approach.

eLife·2026
查看所有相关文章

相关实验视频

Updated: May 16, 2025

Generation of Dispersed Presomitic Mesoderm Cell Cultures for Imaging of the Zebrafish Segmentation Clock in Single Cells
10:41

Generation of Dispersed Presomitic Mesoderm Cell Cultures for Imaging of the Zebrafish Segmentation Clock in Single Cells

Published on: July 24, 2014

13.7K

分段时钟的模块性和形态发生.

James E Hammond1, Ruth E Baker2, Berta Verd1

  • 1Biology Department, University of Oxford, Oxford, United Kingdom.

eLife
|April 1, 2025
PubMed
概括
此摘要是机器生成的。

细分时钟和前somitic mesoderm (PSM) 形态发生在发育上是模块化的,这解释了脊椎动物的干部细分数的演变. 这种模块化允许这些关键发展过程的独立演变.

关键词:
基于代理的模型基于代理的模型.进化 演化 演化 演化 演化 演化 演化 演化它们的可进化性.形态发生 (morphogenesis) 是一种形态的产生.生物系统的物理生活系统的物理.在前索米特性中皮层中形成的前索米特性.索米托基尼斯 (somitogenesis) 是一种体质的产生.斑马鱼是一种斑马鱼.

更多相关视频

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
11:52

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Published on: February 9, 2017

5.9K
An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
07:59

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

7.6K

相关实验视频

Last Updated: May 16, 2025

Generation of Dispersed Presomitic Mesoderm Cell Cultures for Imaging of the Zebrafish Segmentation Clock in Single Cells
10:41

Generation of Dispersed Presomitic Mesoderm Cell Cultures for Imaging of the Zebrafish Segmentation Clock in Single Cells

Published on: July 24, 2014

13.7K
Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
11:52

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Published on: February 9, 2017

5.9K
An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
07:59

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

7.6K

科学领域:

  • 发育生物学是发展生物学.
  • 进化生物学是进化的生物学.
  • 计算生物学是一种计算生物学.

背景情况:

  • 脊椎动物的干部部分数量表现出显著的多样性,但其进化能力尚不清楚.
  • 细分数由前体质质膜 (PSM) 形态发生和细分时钟,PSM内的分子振荡器决定.

研究的目的:

  • 调查细分时钟和PSM形态发生是否在发育上是模块化的.
  • 了解这种潜在的模块化如何有助于脊椎动物细分数的演变.

主要方法:

  • 使用了细分时钟和PSM的计算模型.
  • 参数化了斑马鱼的模型.
  • 在形态遗传过程中模拟的变异,如细胞进入,移动性,紧缩和分裂.

主要成果:

  • 分段时钟显示出对PSM形态遗传过程变异的稳定性.
  • PSM长度和细分时钟相合强度影响了时钟强度.
  • 以前的研究表明,当扰乱时钟时,形态发生没有显著的变化.

结论:

  • 分段时钟和PSM形态发生表现出发育模块化.
  • 这种模块化支持这样的假设,即这些过程的独立进化是脊椎动物细分数的进化能力的基础.