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Updated: May 16, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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PHLPP2是一种伪酸酶,在甲状动物祖先中失去了活性

Tarik Husremović1, Vanessa Meier1, Lucas Piëch1,2

  • 1Max Perutz Labs, University of Vienna and Medical University of Vienna, Vienna 1030, Austria.

Proceedings of the National Academy of Sciences of the United States of America
|April 1, 2025
PubMed
概括

PHLPP2缺乏催化活性,是一种伪酸酶,挑战其作为瘤抑制剂的作用. 研究应该集中在PHLPP1和PHLPP2上.

关键词:
标签: 活动 活动 活动PHLPPPP PHLPPPP 这是一个很好的选择.癌症 癌症 癌症 癌症 癌症酸酶是一种酸酶.信号传输 信号传输

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