压针治疗改善视觉功能和眼睛血液循环的效果和安全性 控制眼内压力的大眼患者:多中心随机对照试验的研究方案
Hongji Liu1, Yan Dai1, Ming Yu1
1Department of Ophthalmology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, Sichuan, China.
JMIR research protocols
|April 1, 2025
概括
压针疗法显示,它有望在控制眼内压力 (GPCI) 的青光眼患者中保护视神经. 这项研究评估了其安全性和有效性,通过增强眼睛血液流动来改善视觉功能.
科学领域:
- 眼科医生 眼科 眼科
- 传统中国医药 传统中国医药
- 针研究 针研究
背景情况:
- 玻璃眼是全球不可逆转失明的主要原因,其特点是逐渐损伤视神经.
- 视神经的保护对于玻璃眼癌的治疗至关重要,但有效的药物仍然有限.
- 压针治疗是一种TCM的外部治疗方法,为保护视神经提供一种安全,符合针治疗的替代方案.
研究的目的:
- 评估压针治疗在控制眼内压力 (GPCI) 的玻璃眼病患者的安全性和临床疗效.
- 为了调查压针治疗是否通过调节眼部血液循环来改善视觉功能.
主要方法:
- 一项随机对照试验,涉及192名参与者 (18至75岁) 用GPCI.
- 参与者被分配1:1接受压针治疗或假压针治疗4周.
- 主要结果:最佳校正的视力敏度 (BCVA),光学连贯性断层扫描血管造影 (OCTA),彩色多普勒流成像 (CDFI),视野评估. 二次结果:眼内压 (IOP),TCM症状尺度.
主要成果:
- 截至2024年10月,招聘超过预测,有192名参与者 (87.3%的完成率).
- 研究的优点包括严格的数据收集,高保留率和优秀的患者遵守.
- 预计最终结果将于2025年9月公布,并有可能进一步分析跨层次相互作用.
结论:
- 这项研究将提供关于压针治疗对GPCI患者视觉功能和眼球循环的影响的关键数据.
- 结果旨在验证针在通过眼部循环调节改善视觉功能的作用.
- 这些发现可能支持治疗GPCI的更广泛的临床应用.
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