相关实验视频

Updated: Jun 12, 2025

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease
10:16

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease

Published on: December 20, 2017

8.0K

Glc-1,6-P2调节对突变的基基酶-2的有益作用

Maria Monticelli1, Debora Paris2, Maria Chiara Monti3

  • 1Institute of Biomolecular Chemistry, National Research Council of Italy, Comprensorio Olivetti, via Campi Flegrei 34, 80078 Pozzuoli, Italy; Dept. Biology, University of Napoli "Federico II", Complesso Universitario Monte Sant'Angelo, via Cinthia, 80126 Naples, Italy.

Biochimica et biophysica acta. Molecular cell research
|April 1, 2025
PubMed
概括

葡萄糖-1,6-双酸盐 (Glc-1,6-P2) 增强PMM2-CDG患者细胞中的糖化作用. 增加Glc-1,6-P2水平显示出治疗这种先天性糖化乱的潜力.

关键词:
生物标志物 生物标志物葡萄糖-1,6-双酸盐是一种格莱科米克斯 (Glycomics) 是一个有趣的药物.代谢学 代谢学 代谢学这就是PMM1的原因.这就是PMM2-CDG.蛋白质组学是指蛋白质组学.

更多相关视频

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases09:13

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases

Published on: November 22, 2024

1.3K
Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays09:36

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays

Published on: August 13, 2017

6.7K

相关概念视频

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.5K
GPCRs Regulate Adenylyl Cylase Activity01:09

GPCRs Regulate Adenylyl Cylase Activity

Some GPCRs transmit signals through adenylyl cyclase (AC), a transmembrane enzyme. AC helps synthesize second messenger cyclic adenosine monophosphate (cAMP). AC catalyzes cyclization reaction and converts ATP to cAMP by releasing a pyrophosphate. The pyrophosphate is further hydrolyzed to phosphate by the enzyme pyrophosphatase, which drives cAMP synthesis to completion. However, cAMP is rapidly degraded to 5′ AMP by the enzymes phosphodiesterase (PDE), preventing overstimulation of...
5.3K