创新药物的替代支付模式:有效实施的框架
Frederick McElwee1,2, Amanda Cole3, Gomathi Kaliappan4
1Office of Health Economics, 2nd Floor Goldings House, Hay's Galleria, 2 Hay's Lane, London, SE1 2HB, UK.
Applied health economics and health policy
|April 1, 2025
概括
本研究介绍了选择和实施替代支付模式 (APM) 的框架,以应对医疗保健价值评估和患者获取药物的挑战. 它指导付款人和制造商寻求具有成本效益的解决方案和创新激励措施.
科学领域:
- 卫生经济学 卫生经济学
- 制药政策 制药政策
- 基于价值的医疗保健
背景情况:
- 科学进步在评估新药的价值,负担能力和患者获取新药方面带来了挑战.
- 现有的付款人挑战需要创新的解决方案,超越传统的支付结构.
- 目前缺乏选择和实施替代支付模式 (APM) 的全面框架.
研究的目的:
- 为有效选择和实施APM提出一个基于证据的,逐步的框架.
- 引导付款人和制造商将合同挑战与适当的APM解决方案结合起来.
- 促进患者更好地获得具有成本效益的药物,并激励未来的创新.
主要方法:
- 使用决策指南识别和映射潜在APM解决方案的合同挑战.
- 主要问题的分类 (预算影响,价值不确定性,谈判范围) 和子类 (负担能力,有效性不确定性,患者异质性).
- 评估解决方案的可行性,利益相关方的合作,并使用最近的APM示例分析实施障碍.
主要成果:
- 制定决策指南,将预算影响和价值不确定性等核心问题映射到APM解决方案 (例如基于结果的协议,订阅模型) 中.
- 该框架强调可行性评估和合作,以成功达成APM协议和实施.
- 现实世界的例子表明,通过务实设计和协作克服常见的实施障碍.
结论:
- 拟议的框架有助于付款人和制造商有效地识别,同意和实施APM.
- 成功实施APM可以提高患者获得经济有效药物的机会.
- 该框架支持继续制药创新的适当激励措施.
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