在研究中包括贫困人口的重要性
Kayla R Mehl1, Stephanie R Morain2,3, Emily A Largent4
1Johns Hopkins Berman Institute of Bioethics, 2129 Ashland Avenue, Baltimore, MD, 21205, USA. kmehl2@jh.edu.
Pharmaceutical medicine
|April 1, 2025
概括
将服务不足的人群纳入临床试验对于研究公平性和有效的医疗保健至关重要. 解决诸如获取和参与等障碍,有助于促进健康公平.
科学领域:
- 临床试验 临床试验
- 健康 公平 卫生 公平
- 研究伦理学研究伦理学
背景情况:
- 缺乏服务的群体面临着系统性障碍,无法获得医疗保健和参与研究.
- 在临床试验中缺乏代表性破坏了研究公平性和包容性医疗保健发展.
- 包容对于正义,发现的概括性和建立对医疗机构的信任至关重要.
研究的目的:
- 为包括服务不足的人群在后期临床试验中的伦理考虑提供概述.
- 将服务不足的人群与其他群体 (弱势群体,少数群体,代表性不足) 区分开来.
- 探索特定服务不足群体的障碍和有针对性的解决方案.
主要方法:
- 审查伦理考虑和参与研究的障碍.
- 针对农村居民,种族/少数民族,低收入人士和老年人,确定有针对性的解决方案.
- 分析改善参与的策略.
主要成果:
- 关键的障碍包括限制访问的系统,后勤和社会因素.
- 有效的策略包括可访问的试验场所,降低财务/物流负担,更广泛的资格和文化定制的宣传.
- 跨部门和特定背景的战略是必不可少的,需要多个利益相关者的合作.
结论:
- 参与策略的广泛实施代表了朝着推进健康公平的有意义的步骤.
- 解决研究中的代表性不足问题是解决医疗保健不平等问题的关键组成部分.
- 定制,协调的努力是必要的,以确保公平的研究包容.
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