PLA2G7通过JAK-STAT-PDL1轴促进膀癌的免疫逃避

Ding Peng1, Wuping Yang1, Tianyu Tang1

  • 1Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, Zhejiang Province, 310003, PR China.

Cell death & disease
|April 1, 2025
PubMed
概括

脂酶A2第七组 (PLA2G7) 在膀癌中升高,促进瘤生长和PD-L1表达. 向PLA2G7通过增强T细胞透和与其他疗法协同作用,提供了一种新的免疫疗法策略.

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