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相关概念视频

Clinical Trials01:16

Clinical Trials

6.6K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
6.6K
Hazard Ratio01:12

Hazard Ratio

72
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
72
Purpose of Health Records II01:19

Purpose of Health Records II

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Health records serve various essential purposes in the healthcare system. Here are some key purposes:
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Methods of Documentation VII: EMR01:30

Methods of Documentation VII: EMR

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Electronic Medical Records (EMRs) primarily center around electronically documenting patients' health information within a single healthcare organization or practice. They contain essential clinical data related to a patient's medical history, diagnoses, medications, treatment plans, lab results, and other pertinent information relevant to the specific encounter or episode of care. EMRs are designed to streamline documentation and workflow processes within individual healthcare...
784
Health Information Technology and Healthcare Information System01:30

Health Information Technology and Healthcare Information System

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Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
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相关实验视频

Updated: May 16, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

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重新利用基于HL7CDA的共享EHR系统的数据进行临床试验:分析可行性的一种方法.

Georg Duftschmid1, Florian Katsch2,3, Gabriela Ciortuz4

  • 1Center for Medical Data Science (CEDAS), Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria. georg.duftschmid@muv.ac.at.

BMC medical informatics and decision making
|April 1, 2025
PubMed
概括

共享电子健康记录 (EHR) 系统可以支持临床试验. 一种新的方法表明,这些系统涵盖了大多数所需的数据元素,其中77%是结构化的,用于试验重复使用.

关键词:
临床试验中的临床试验.数据收集 数据收集数据模型数据模型电子医疗记录电子医疗记录

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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

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相关实验视频

Last Updated: May 16, 2025

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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
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A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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科学领域:

  • 医疗信息学 医疗信息学
  • 临床试验管理 临床试验管理
  • 数据标准 数据标准

背景情况:

  • 电子健康记录 (EHR) 系统对于临床试验数据的再利用非常有价值.
  • 虽然共享的EHR系统普遍存在,但在试验中未得到充分利用.
  • 对于临床试验要求的共享EHR系统的数据覆盖范围尚不清楚.

研究的目的:

  • 介绍一种分析临床试验数据元素覆盖范围的共享电子健康记录系统的方法.
  • 评估共享EHR系统对临床试验进行的适用性.

主要方法:

  • 专注于HL7 CDA标准化的共享EHR系统.
  • 使用EHR4CR参考列表来获得常见的临床试验数据元素.
  • 使用ART-DECOR进行半自动映射和额外的开源分析工具.

主要成果:

  • 开发了一种逐步方法来分析HL7基于CDA的共享EHR系统.
  • 让所有工具和映射公开可用,以便可重复使用和重复复制.
  • 将该方法应用于奥地利的ELGA系统,发现88%的EHR4CR数据元素覆盖率 (77%结构化).

结论:

  • 该方法可以轻松分析共享EHR系统的临床试验数据重复使用潜力.
  • 针对ELGA的结果显示了临床试验数据整合的巨大潜力.