在儿童期化物暴露后,预防牙和神经发育障碍风险
1Institute of Chronic Illnesses, Inc, 14 Redgate Ct, Silver Spring, MD, 20905, USA.
BMC pediatrics
|April 1, 2025
概括
化水可能会略微降低牙的风险,但与儿童神经发育障碍的风险略微增加有关. 建议进行进一步的风险效益分析.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 环境健康 环境健康
背景情况:
- 化水被认为是20世纪公共卫生的一个重大成就.
- 疾病控制和预防中心 (CDC) 强调了它的重要性.
- 这项研究调查了化水对牙和神经发育障碍的双重影响.
研究的目的:
- 评估儿童水化暴露与牙腐烂风险之间的关系.
- 评估儿童水化暴露与神经发育障碍风险之间的关联.
- 为未来的水化政策的风险效益分析提供信息.
主要方法:
- 使用佛罗里达州医疗补助数据 (1990-2012) 的纵向队列研究.
- 研究了73,254名儿童在生命的头10年.
- 以共变量调整的统计建模 (物流和频率),分析县级化水暴露.
主要成果:
- 出生年份的化物暴露与牙腐烂风险略有降低有关,这取决于剂量.
- 化物暴露还与自闭症谱系障碍 (ASD),注意力缺陷多动症障碍 (ADHD),智力障碍 (ID) 和特定发育迟缓 (SDD) 的风险略有增加有关.
- 与没有接触过化水的儿童相比,在最初的10年内接触过化水的儿童的牙腐烂风险明显较低,但ASD,ID和SDD风险明显更高.
结论:
- 这项研究表明,化水和儿童健康结果之间存在复杂的关系.
- 研究结果表明,这种药物既能防止牙腐烂的保护作用,也可能增加某些神经发育障碍的风险.
- 鉴于这些发现,需要对水化进行更新的风险效益分析.
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