母亲的氧气吸入会影响胎儿的血液动力学,在低风险,没有并发症的晚期怀孕中
Xiu-Qin Wu1, Xiao-Feng Yang1, Lin Ye1
1Department of Ultrasound, Mindong Hospital Affiliated to Fujian Medical University, Fujian, China.
European journal of medical research
|April 1, 2025
概括
怀孕后期母亲吸入氧气可能会对胎儿健康产生负面影响,导致胎盘脉动率指数 (PPI) 高,脑胎盘比率 (CPR) 低. 这些变化表明对胎儿的潜在不良结果.
科学领域:
- 产周医学 产周医学
- 胎儿生理学 胎儿生理学
- 产科超声波 产科超声波 产科超声波
背景情况:
- 产妇在分娩期间的氧气治疗缺乏经过证明的新生儿益处,其对妊娠后期胎儿血液动力学的影响尚不清楚.
- 这项研究解决了围绕母亲吸入氧气对胎儿在第三个三个月的幸福感的影响的不确定性.
研究的目的:
- 为了研究母亲在怀孕后期吸入氧气和胎儿血液动力学变化之间的联系.
- 评估母体氧气给药对胎儿多普勒参数的短期影响.
- 评估母亲吸入氧气对胎儿的潜在益处或风险.
主要方法:
- 对单子妊娠的回顾性分析,在怀孕32周后接受产前超声波.
- 接受母体氧气吸入 (3L/分钟30分钟) 的组与没有氧气的组之间的比较.
- 主要结局包括胎盘脉动性指数 (PPI) 和脑胎盘比率 (CPR),胎儿心脏功能通过多普勒和M模式进行评估.
主要成果:
- 母亲的氧气吸入与明显更高的PPI (0.81±0.12对比0.76±0.11) 和较低的心肺复苏 (1.98±0.56对比2.28±0.70) 相关.
- 在氧气吸入组中,出生体重也显着较低 (2983.78 ± 468.18g vs 3178.41 ± 477.59g).
- 在各种母体和胎儿动脉或静脉的抵抗指数中没有发现显著差异.
结论:
- 孕妇在孕期第三季度短暂吸入氧气与胎儿血液动力学不良变化有关,PPI升高和心肺复苏降低表明了这一点.
- 这些多普勒衍生指数表明,母亲吸入氧气可能会对胎儿健康产生负面影响.
- 建议在考虑为孕妇,特别是那些高风险怀孕的孕妇提供氧气时,仔细评估和监测多普勒指数.
相关概念视频
01:14Fetal Circulation
653
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
653
01:19Respiratory Assessment: Purpose and Indications
982
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
982
01:27Oxygen Transport in the Blood
2.3K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
2.3K
01:23Physiological Control of Respiration
1.8K
Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
1.8K
01:21Acute Respiratory Failure-II
151
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
151
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
131
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
131