相关实验视频

Updated: Jun 13, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
11:19

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 26, 2011

利基-tRNA-合成酶 (LeuRS) 的时间依赖抑制:洞察目标脆弱性

Mingqian Wang1, YongLe He1, Siobhan A Cohen1

  • 1Center for Advanced Study of Drug Action, and Department of Chemistry, Stony Brook University, Stony Brook, New York 11794-3400, United States.

ACS infectious diseases
|April 2, 2025
PubMed
概括

本佐xaboroles通过准leucyl-tRNA合成酶来抑制细菌蛋白质合成. 将它们与托布拉米辛结合,通过减少酶合成来增强后抗生素效应 (PAE),提供新的剂量策略.

关键词:
没有工作的劳动力.莱维基-tRNA-合成酶的作用在这里,pSILAC.后抗生素效应的后抗生素效应居住时间 居住时间针对目标漏洞进行攻击.

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