在多发性硬化症中,生物性别,认知储备和认知之间的关系
Manuela Altieri1,2, Alvino Bisecco1, Alessandro d'Ambrosio1
1Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
概括
认知储备和生物性别独立地影响多发性硬化症 (MS) 的认知表现. 这两个因素对评估至关重要,定制培训可以增强所有多发性硬化症患者的认知储备.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 康复医学 康复医学 康复医学
背景情况:
- 认知障碍在多发性硬化症 (MS) 中很普遍.
- 生物性别和认知储备 (CR) 是潜在的影响因素.
- 在MS中性别,CR和认知之间的相互作用需要进一步研究.
研究的目的:
- 检查认知储备 (CR) 发育中的性别差异.
- 确定性别和CR对MS患者认知表现的独立和互动影响.
主要方法:
- 233名参与者完成了神经心理测试 (BRB-N,Stroop) 和认知储备量表.
- T测试比较了性别之间的社会人口统计学,CR和认知变量.
- 共同变量的多变量分析评估了性别和CR对认知的影响,控制年龄,残疾和情绪.
主要成果:
- 女性报告CR更高,特别是在日常活动,爱好和社交生活中.
- 观察到基于性别的认知差异:女性在口头记忆/流利方面表现出色,男性在处理速度方面表现出色.
- 没有发现CR和性别对认知表现的显著相互作用.
结论:
- 认知储备和生物性别似乎在MS患者中独立地影响认知功能.
- 这两个因素都是MS认知评估中的重要考虑因素.
- 针对CR增强的精神教育干预措施可能对两性都有好处.
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