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相关概念视频

Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

6.2K
Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
6.2K
Peptide Bonds02:43

Peptide Bonds

71.6K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
71.6K

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相关实验视频

Updated: May 16, 2025

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
13:37

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

Published on: June 20, 2014

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:一种轻量级的Python库,用于机器学习中的体表示.

Rıza Özçelik1,2, Laura van Weesep1, Sarah de Ruiter1

  • 1Department of Biomedical Engineering, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven 5612AZ, Netherlands.

Bioinformatics advances
|April 2, 2025
PubMed
概括
此摘要是机器生成的。

介绍peptidy,一个用于将序列转换为机器学习的数值格式的Python库. 该工具支持各种编码策略和翻译后修改,加速类研究.

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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

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Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein
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Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein

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相关实验视频

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Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

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Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein
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Overlapping Peptide Library to Map Qa-1 Epitopes in a Protein

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科学领域:

  • 计算生物学 计算生物学
  • 生物信息学是一种生物信息学.
  • 机器学习 机器学习

背景情况:

  • 在药物发现和食品科学中至关重要.
  • 机器学习加速了类研究.
  • 需要用户友好的计算工具.

研究的目的:

  • 介绍peptide,一个用于化成数字表示转换的Python库.
  • 促进机器学习应用在化物研究中.
  • 支持各种编码策略和翻译后修改.

主要方法:

  • 开发了一个名为peptidy的轻量级Python库.
  • 对序列实施了各种编码策略.
  • 包括对翻译后修改 (酸化,乙化,甲基化) 的支持.

主要成果:

  • 可以无地将转换为机器学习准备的数值格式.
  • 该库没有依赖性,并且可以轻松集成到Python环境中.
  • 具有翻译后修改的的扩展功能.

结论:

  • 增强了用于发现和设计的机器学习方法.
  • 该图书馆为计算研究提供了一种多功能工具.
  • peptidy 在 GitHub 上以许可许可许可证提供.