在保加利亚,多发性硬化症的流行和发病率
Antonia Nikolova1,2, Ivan Milanov1,2, Ksenia Kmetska1,2
1Department of Neurology, Medical University, Sofia, Bulgaria.
Frontiers in neurology
|April 2, 2025
概括
这项研究发现,保加利亚的多发性硬化症 (MS) 患病率很高,患病率为121.2/100,000,发病率为4.2/100,000. 调查结果显示,与之前的研究相比,增幅有所增加,保加利亚处于高频率多发性硬化症地区.
科学领域:
- 流行病学 流行病学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性,炎症性,自身免疫性,脱髓性和神经退行性中枢神经系统疾病.
- 多发性硬化主要影响年轻人,是不可逆转的神经缺陷的主要原因.
- 这种疾病在全球地理分布不均.
研究的目的:
- 估计保加利亚多发性硬化症的流行率和发病率.
- 分析MS的分布,根据年龄和性别.
- 确定保加利亚MS患者的临床特征.
主要方法:
- 从2015年到2021年,在保加利亚进行了一项流行病学研究.
- 使用了国家统计局的数据和个别问卷.
- 2017年麦当劳诊断标准适用于所有多发性硬化病例.
主要成果:
- 在2021年9月7日,患病率为121.2/100,000,发病率为4.2/100,000.
- 总共发现了532例多发性硬化病例,女性与男性的比例为2:1.
- 疾病发病时的平均年龄为32.2岁,超过50%的人经历了复发缓解的过程.
结论:
- 保加利亚显示MS的高频率,与以前的研究相比,患病率和发病率增加.
- 这些发现与邻近的巴尔干国家和欧洲平均水平一致.
- 这项研究提供了保加利亚多发性硬化症的最新流行病学数据.
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