急性和长期COVID-19的负担:巴林的一项全国性研究
Mariam Murad1, Stephen L Atkin1, Pearl Wasif1
1Royal College of Surgeons in Ireland, Al Muharraq, Bahrain.
Frontiers in public health
|April 2, 2025
概括
后COVID-19条件 (PCC) 影响超过1000个人,特别是具有危险因素的老年女性. 接种疫苗对于预防SARS-CoV-2并发症和COVID-19后的疾病至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 可能导致长期的健康问题,称为后续.
- 了解SARS-CoV-2感染的急性和后急性影响对于公共卫生战略至关重要.
- 识别患有COVID-19后疾病 (PCC) 风险较高的人群对于有针对性的干预至关重要.
研究的目的:
- 评估巴林人口中SARS-CoV-2感染的急性和后急性负担.
- 确定与COVID-19后疾病发展相关的人口和临床因素.
- 分析不同流行病激增期间急性COVID-19和PCC的发病率和死亡率.
主要方法:
- 从2021年5月到2023年4月,使用巴林国家行政数据库进行了回顾性观察研究.
- 根据世界卫生组织 (WHO) 的指导方针确定了COVID-19后病例.
- 所有COVID-19病例都通过实时聚合酶链反应 (PCR) 测试得到证实.
主要成果:
- 在13067名COVID-19病例中,有1045人患有PCC. 患有PCC的个体通常是老年妇女,具有先前存在的风险因素和SARS-CoV-2再感染史.
- PCC的发病率从阿尔法到Omicron的激增 (0.27到19.3每10万人) 显著增加.
- 在急性COVID-19和PCC的三角洲疫情激增期间,65岁及以上的个体的死亡率最高.
结论:
- 建议在新的COVID-19激增之前及时进行国家疫苗接种计划,以减轻并发症.
- 接种疫苗可以帮助预防严重的后果和COVID-19后的情况,特别是在脆弱人群中.
- 专注于老年人和有风险因素的个人是减轻SARS-CoV-2感染及其后果负担的关键.
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