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Updated: Jun 13, 2025

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酸化诱导的SUMOylation促进Ulk4在状尖端的凝聚,以转化刺信号

Mengmeng Zhou1, Yuhong Han1, Jin Jiang1,2

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Journal of cell science
|April 2, 2025
PubMed
概括

刺 (Hh) 信号传递涉及Stk36和Ulk4激酶,它们调节了主要尖的Gli2蛋白凝聚. 这一由酸化和SUMOylation驱动的过程对于在发育和组织修复过程中激活Hh通路至关重要.

关键词:
这是一个很棒的节目,Gli Gli Gli.刺是一只刺.酸化是指酸化的方法.主要的纤毛是主要的纤毛.这就是SUMOylation的作用.在 Ulk4 中,我们可以使用 Ulk4.

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